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Vitamin
C, is also known as ascorbic acid, and is probably one of the least understood
of all of the vitamins.
Vitamins
are organic (carbon containing) molecules that mainly function as catalysts for
reactions within your body. A catalyst is a substance that allows a chemical
reaction to occur using less energy and less time than it would take under
normal conditions. If these catalysts are missing, as in a vitamin deficiency,
normal body functions can break down and make a person susceptible to disease.
It
is interesting to note that most animals produce their own vitamin C. Humans,
primates (apes, chimps, etc.) and guinea pigs have lost this ability. Vitamin C
is important to all animals, including humans, because it is vital to the
production of collagen. Vitamin C is also important because it helps protect the
fat-soluble vitamins A and E as well as fatty acids from oxidation. Vitamin C
prevents and cures the disease scurvy, and can be beneficial in the treatment of
iron deficiency anemia.
Collagen
is the most ubiquitous substance in the body because it is the most abundant of
the fibers contained in connective tissue. Connective tissue gives your body
form and supports your organs. To give you an idea of how important collagen is,
here is a list of the five types of collagen, and where they are used in the
body.
-
Type
1 - Connective tissue of skin, bone, teeth, tendons, ligaments, fascia,
organ capsules
-
Type
2 - Cartilage
-
Type
3 - Connective tissue of our
organs (liver, spleen, kidneys, etc.)
-
Type
4/5 - The separating layer
between epithelial and endothelial cells as well as between skeletal or smooth
muscle cells (basal lamina), kidney glomeruli, lens capsule, and Schwann and
glial cells of the nervous system.
As you can see, collagen is everywhere in your body, and
vitamin C plays a role in the formation of collagen.
When
collagen is produced, there is a complex series of events, some occurring inside
of the cell, and some outside of the cell. Vitamin C is active inside of the
cell, where it hydroxylates (adds hydrogen and oxygen) to two amino acids:
proline and lysine. This helps form a precursor molecule called procollagen that
is later packaged and modified into collagen outside of the cell. Without
vitamin C, collagen formation is disrupted, causing a wide variety of problems
throughout your body.
A
deficiency of vitamin C causes the disease Scurvy. Scurvy is rarely seen today
except in alcoholics who receive their entire calorie intake from alcohol.
Scurvy causes bleeding and inflamed gums, loose teeth, poor wound healing, easy
bruising, bumps of coiled hair on the arms and legs, pain in the joints, muscle
wasting, and many other problems.
Vitamin
C is found in citrus fruits such as oranges, limes, and grapefruit, and
vegetables including tomatoes, green pepper, potatoes and many others. Vitamin C
is easily damaged during food preparation, such as chopping, exposure to air,
cooking, boiling, and being submerged in water. The amount of Vitamin C is high
enough in most foods that the quantity that remains after processing is usually
more than enough for your daily supply.
The
recommended dietary allowance (RDA) of vitamin C is 60 milligrams per day. As
little as 5-7 mg a day will prevent scurvy, and the average American gets about
72 mg a day, more than enough. Also, the liver stores about a 3 months supply of
vitamin C as well.
High
doses of vitamin C can cause a number of serious health consequences, including:
-
A toxic release of inorganic iron, which can be potentially
fatal in some people
-
Formation of oxalate kidney stones
-
Diarrhea
-
Rebound
scurvy if the vitamin is abruptly stopped
-
Damage to the outer layer of the teeth (enamel) if the
tablets are chewed
-
Abnormal heart rhythms
One
myth about vitamin C is that it is an antioxidant, but that is not completely
true. Vitamin C is a redox agent, meaning that it acts as an antioxidant in some
cases, and an oxidant in others. Antioxidants are important because they inhibit
chemical reactions with oxygen or highly reactive free radicals. These reactions
(oxidation reactions), cause damage to cells. Vitamin C only acts as an
antioxidant in some circumstances.
Vitamin
C is an important part of a healthy diet. It is not a miracle drug, and can
cause harm if taken in excess. A well-balanced, varied diet will ensure that you
receive more than enough vitamin C to prevent scurvy and other potential health
problems.
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